We’re teaching Population and Quantitative Genetics (undergrad EVE102) this quarter. We’re posting our materials here, in case they are of interest.
A pdf of the popgen notes is here
The slide pdfs are linked to below
Lecture One [Introduction and HWE]. Reading notes up to end of Section 1.2.
lecture_2_rellys_inbreeding [HWE, Relatedness (IBD), Inbreeding loops] Read Sections 1.3-1.5
lecture_3_population structure [Inbreeding, FST and population structure]
1/2 class Reading Discussion Simons Genome Diversity Project and Kreitman 1983 + 1/2 class on lecture_4 [Other common approaches to population structure, Section 1.7 of Notes optional reading]
lecture_5_ld_drift [Linkage Disequilibrium + Discussion of Neutral Polymorphism] Reading Section 1.8 of notes.
lecture_6_drift_loss_of_heterozygosity[Genetic Drift & mutation, effective population size. Read Chapter 2, up to end of Section 2.3]
Lecture 7. Finishing up lecture 6 & Discussion of Canid paper.
lecture_8_coalescent. [Pairwise Coalescent & n sample Coalescent. Read Notes Section 24-2.5].
lecture_9_coalescent_demography [Non-constant population size, and demography inference].
Lecture 10: Midterm 1.practice_problems_1_2016
lecture_10_pop_struct_divergence [demography, pop-structure, divergence. Read sections 2.6-2.7 of notes].
lecture_11_divergence [Molecular Clock, Neutral theory, MK test]
lecture_12_ILS [incomplete lineage sorting, reading & discussion of Li & Durbin]
lecture_13_abba_baba_quantgen [ABBA-BABA & quantitative genetics]
lecture_14_quantgen [heritability and response to selection]
lecture_15_sel_mult_traits [Long term response, interpretations of breeder’s eqn. & Correlated traits]
lecture_16_tradeoffs_indirect_benefits[Correlated traits, Sexual selection]
lecture_17_1_locus_models [1 locus popgen selection model]
lecture_18_directional_sel_balancing_sel [directional & heterozygote advantage]
lecture_19_balsel_mutsel_balance[-ve frequency dependence, mutation selection balance, inbreeding depression]
lecture_20_migsel_seldrift [Migration-selection balance, Drift-Selection interaction]
lecture_21_seldrift [Nearly Neutral Theory]
lecture_23_selection_rec [interaction between selection & recombination]
lecture_24_supergenes_sex [inversions & supergenes, short-term benefits and long term costs of asexual reproduction]
lecture_25_sex_chromosomes_selfish_elements [sex chromosomes, sex ratio, sex ratio distortors]
lecture_26_selfish_elements [Selfish elements, selection below level of gene]
lecture_27_speciation [The population genetics of Speciation & Hybrid zones]