Population Genetics Undergrad Class

We’re teaching Population and Quantitative Genetics (undergrad EVE102) this quarter. We’re posting our materials here, in case they are of interest.

A pdf of the popgen notes is here

The slide pdfs are linked to below

Lecture One [Introduction and HWE]. Reading  notes up to end of Section 1.2.

lecture_2_rellys_inbreeding  [HWE, Relatedness (IBD), Inbreeding loops] Read Sections 1.3-1.5

lecture_3_population structure [Inbreeding, FST and population structure]

1/2 class Reading Discussion Simons Genome Diversity Project and Kreitman 1983 + 1/2 class on  lecture_4 [Other common approaches to population structure, Section 1.7 of Notes optional reading]

lecture_5_ld_drift [Linkage Disequilibrium + Discussion of Neutral Polymorphism] Reading Section 1.8 of notes.

lecture_6_drift_loss_of_heterozygosity[Genetic Drift & mutation, effective population size. Read Chapter 2, up to end of Section 2.3]

Lecture 7. Finishing up lecture 6 & Discussion of Canid paper.

lecture_8_coalescent. [Pairwise Coalescent & n sample Coalescent. Read Notes Section 24-2.5].

lecture_9_coalescent_demography [Non-constant population size, and demography inference].

Lecture 10: Midterm 1.practice_problems_1_2016

lecture_10_pop_struct_divergence [demography, pop-structure, divergence. Read sections 2.6-2.7 of notes].

lecture_11_divergence [Molecular Clock, Neutral theory, MK test]

lecture_12_ILS [incomplete lineage sorting, reading & discussion of Li & Durbin]

lecture_13_abba_baba_quantgen [ABBA-BABA & quantitative genetics]

lecture_14_quantgen [heritability and response to selection]

lecture_15_sel_mult_traits [Long term response, interpretations of breeder’s eqn. & Correlated traits]

lecture_16_tradeoffs_indirect_benefits[Correlated traits, Sexual selection]

lecture_17_1_locus_models [1 locus popgen selection model]

lecture_18_directional_sel_balancing_sel [directional & heterozygote advantage]

lecture_19_balsel_mutsel_balance[-ve frequency dependence, mutation selection balance, inbreeding depression]

lecture_20_migsel_seldrift [Migration-selection balance, Drift-Selection interaction]

lecture_21_seldrift [Nearly Neutral Theory]

lecture_22_hitchhiking [Hitchhiking]

lecture_23_selection_rec [interaction between selection & recombination]

lecture_24_supergenes_sex [inversions & supergenes, short-term benefits and long term costs of asexual reproduction]

lecture_25_sex_chromosomes_selfish_elements [sex chromosomes, sex ratio, sex ratio distortors]

lecture_26_selfish_elements [Selfish elements, selection below level of gene]

lecture_27_speciation [The population genetics of Speciation & Hybrid zones]





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4 Responses to Population Genetics Undergrad Class

  1. Shabbeer Hassan says:

    Thanks a lot for sharing the lecture slides. This is nice material to transition to Felsenstein’s notes on evol gen and Ewens notes on pop gen.

  2. Shabbeer Hassan says:

    Reblogged this on Science Geek and commented:
    A nice bunch of notes for learning a wee bit of population genetics. Covers recent advances in pop gen too !

  3. Chenling Xu says:

    I hope it is ok for me to use some of this for an undergrad class I am TAing this semester!

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