Category Archives: teaching

Figures of Genetic Drift

Figures are really useful for explaining concepts like drift, however, I often find textbook figures are not super helpful. Pictures of hands reaching into jam jars of beans etc are useful metaphors but don’t really depict the process of transmission … Continue reading

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GC Williams and Socrates

Thought I’d pull this passage out of GC Williams’s “Adaptation and Natural selection“. I was looking for it the other day, as I’m considering using it in my Evolution class, and couldn’t find it easily via google. “Natural selection of … Continue reading

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Popgen cookies

My wonderful population genetics graduate student class surprised me with popgen inspired cookies for the last class. There’s species trees, trees, frequency spectra & equations and a whole boatload of popgen fun. Thanks to the class for a great set … Continue reading

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How many genomic blocks do you share with a cousin?

Thanksgiving is over, although you fridge may still be full of leftovers. You probably spent your time wondering exactly what you have in common with your cousin, other than your loathing of brussels sprouts. I’m a British ex-pat so I … Continue reading

Posted in genetic genealogy, popgen teaching | 13 Comments

How many genetic ancestors do I have?

In my last couple of posts I talked about how much of your (autosomal) genome you inherit from a particular ancestor [1,2]. In the chart below I show a family tree radiating out from one individual. Each successive layer out … Continue reading

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How much of your genome do you inherit from a particular ancestor?

How much of your genetic material do you inherit from a particular ancestor? You inherit your mitochondria through your matrilineal lineage (your mum, your mum’s mum, your mum’s mum’s mum and so one) and your Y chromosome from your patrilineal … Continue reading

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How much of your genome do you inherit from a particular grandparent?

You’ve got two copies of each chromosome, having received one copy of each chromosome from your mother and one chromosome from your father (this is true for your autosomes, but not for your X, Y, and mitochondria). When it comes … Continue reading

Posted in genetic genealogy, personal genomics, popgen teaching | 37 Comments

couple of notes on fixation prob. of beneficial allele

There was a conversation on twitter about Haldane’s 2s approximation to the fixation probability of an allele, and how it related to the diffusion approximation of the same quantity. This followed from a blog post by Adam Eyre-Walker. I thought … Continue reading

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“Ask me anything” Reddit on our European ancestry paper

Peter Ralph and I are doing an “Ask me anything” on our paper about the Recent genetic genealogy of Europe over at the askScience reddit http://www.reddit.com/r/askscience/comments/1ee560/askscience_ama_we_are_the_authors_of_a_recent/ today [May 15th]. Feel free to pop by and ask us questions.

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Identification of genomic regions shared between distant relatives

We’ve been addressing some of the FAQs on topics arising from our paper on the geography of recent genetic genealogy in Europe (PLOS Biology). We wanted to write one on shared genetic material in personal genomics data but it got … Continue reading

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